The Biology of Innate Lymphoid Cells|
The authors summarize studies that formally identified innate lymphoid cells and highlight their emerging roles in controlling tissue homeostasis in the context of infection, chronic inflammation, metabolic disease and cancer. [Nature] Abstract
Chronic Hepatitis B: Role of Anti-Platelet Therapy in Inflammation Control
The authors discuss major platelet functions in immune and inflammatory responses, with an emphasis on recent pre-clinical studies that suggest that the inhibition of platelet activation pathways represent an alternative therapeutic strategy with potential use in the reduction of virus-specific T cell-mediated chronic inflammation, liver fibrosis and hepatocellular carcinoma in patients who are chronically infected with hepatitis B virus. [Cell Mol Immunol] Abstract
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Roche, Meiji and Fedora Join Forces to Tackle Increasing Bacterial Resistance to Antibiotics|
Roche, Meiji Seika Pharma and Fedora announced that they have entered into a license agreement for the development and commercialization of OP0595, a beta-lactamase inhibitor in Phase I clinical development. [Roche Ltd.] Press Release
Moderna Announces License and Collaboration Agreement with Merck to Develop Messenger RNA-Based Antiviral Vaccines and Passive Immunity Therapies
Moderna Therapeutics announced a license and collaboration agreement with Merck, through a subsidiary, for the discovery and development of vaccines and passive immunity treatments against viral diseases using modified messenger RNA. [Moderna Therapeutics] Press Release
University of Rochester Tests HIV Vaccine Pill
Researchers at the University of Rochester Medical Center are testing a new oral vaccine to prevent infection with HIV, the virus that causes AIDS. The study is funded and designed by Beth Israel Deaconess Medical Center, which received support for a Collaboration for AIDS Vaccine Discovery grant from the Bill & Melinda Gates Foundation. [University of Rochester Medical Center] Press Release
Antitope, INSERM and Baylor Institute for Immunology Research to Collaborate to Produce Manufacturing Cell Lines for Two Novel Vaccines for HIV
Antitope Limited announced that it has extended its relationship with INSERM, the French National Institute of Health and Medical Research; ANRS, the National Health Agency for Research on AIDS and Hepatitis; and the Baylor Institute for Immunology Research. [Antitope Limited] Press Release
Adaptive Biotechnologies Announces Acquisition of Sequenta, Inc.
Adaptive Biotechnologies Corporation announced the acquisition of Sequenta, Inc. which is expected to expedite and expand the use of novel immunosequencing products for researchers and clinicians to diagnose, treat, and monitor patients with cancer, autoimmune disorders, and infectious diseases. [Adaptive Biotechnologies Corporation] Press Release