Researchers Describe How Lungs Stand Guard against the Flu
Researchers describe how different types of immune system cells interact to generate cells in the lungs capable of mounting an effective counterattack on the invading virus, regardless of the types of proteins on the virus’ surface. [Press release from Yale University discussing online prepublication in Immunity] Press Release|Abstract|Graphical Abstract
Early HIV-1 Infection Is Associated with Reduced Frequencies of Cervical Th17 Cells
The impact of early HIV infection on cervical CD4+ T cell populations in humans remains poorly described. Researchers analyzed cytobrush-derived immune cells by flow cytometry and cytokines in cervicovaginal lavage from participants in early HIV, chronic HIV, and HIV uninfected controls. [J Acquir Immune Defic Syndr] Abstract
NK Cell Receptor Imbalance and NK Cell Dysfunction in HBV Infection and Hepatocellular Carcinoma
The authors focus on the role of natural killer (NK) cell receptors in anti-tumor immune responses in hepatocellular carcinoma (HCC), particularly hepatitis B virus (HBV)-related HCC. They discuss specifically how tumor cells evade attack from NK cells and how emerging understanding of NK receptors may aid the development of novel treatments for HCC. [Cell Mol Immunol] Abstract
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SCIENCE NEWS
Genocea Presents Complete Phase I/IIa Data for HSV-2 Immunotherapy at IDWeek
Genocea Biosciences, Inc. announced the presentation of final data from the Phase I/IIa study of GEN-003, the company’s immunotherapy candidate for treatment of genital herpes. [Press release from Genocea Biosciences, Inc. discussing research presented at IDWeek 2014™, Philadelphia] Press Release
Bristol-Myers Squibb Presents Data from Multiple New Studies Showcasing Continued Innovation in Virology
Bristol-Myers Squibb Company announced that ten abstracts have been accepted for presentation. The breadth of data presented highlights Bristol-Myers Squibb’s commitment to discover, develop and deliver innovative medicines that help patients prevail over chronic viral diseases. [Press release from Bristol-Myers Squibb Company discussing research presented at IDWeek 2014™, Philadelphia] Press Release
Durata Therapeutics Presents New Data for Dalvance™
Durata Therapeutics announced a summary of presentation data from its recently launched product, Dalvance™ (dalbavancin) for injection. [Press release from Durata Therapeutics, Inc. discussing research presented at IDWeek 2014™, Philadelphia] Press Release
MOLOGEN AG Presents EnanDIM: A New Generation of Immunomodulators
MOLOGEN has presented preclinical data on its EnanDIM technology. Potential applications include the fields of anti-tumor and anti-infective therapies. [Press release from MOLOGEN AG discussing research presented at the 10th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS), San Diego] Press Release
Johns Hopkins Pediatrician Wins NIH Transformative Research Award
Johns Hopkins Children’s Center infectious disease specialist Sanjay Jain, M.D., has earned a Transformative Research Award from the National Institutes of Health (NIH) for his ongoing work to design a new noninvasive imaging method that can rapidly identify a wide variety of bacterial infections and monitor their response to treatment in real time. [Johns Hopkins University] Press Release
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