Tuberculosis Vaccines – Rethinking the Current Paradigm
Authors review the current understanding of host-pathogen interactions in tuberculosis (TB) infection and propose that rather than boosting T helper 1 responses, researchers should focus on understanding protective immune responses that are lacking or insufficiently promoted by Bacillus Calmette-Guérin that can intervene at critical stages of the TB life cycle. [Trends Immunol]
Relationship between Cytokine Gene Polymorphisms and Chronic Hepatitis B Virus Infection
The current knowledge in the literature on the association between cytokine/regulatory molecule gene polymorphisms and clinical course of chronic hepatitis B virus infection is summarized, and the clinical implementations and future prospects regarding this knowledge are discussed. [World J Gastroenterol]
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