Cellular Immune Controls Over Epstein-Barr Virus Infection: New Lessons from the Clinic and the Laboratory|
Epstein-Barr virus induces multiple cellular immune responses in the infected host. How these host responses work together to prevent virus pathogenicity, and how immune imbalance predisposes to disease, remain poorly understood. Here, the authors describe three ongoing lines of enquiry that are shedding new light on these issues. [Trends Immunol]
New Insights into the Crosstalk between Shigella and T Lymphocytes
The authors focus on the recent advances made in the understanding of how the enteroinvasive bacterium Shigella flexneri interferes with the host adaptive response by targeting T lymphocytes, especially their migration capacities. [Trends Microbiol]
GSK3β and the Control of Infectious Bacterial Diseases
This review focuses on the central role of glycogen synthase kinase 3β (GSK3β) in the regulation of pathogen-induced inflammatory responses through the regulation of pro- and anti-inflammatory cytokine production, the extensive ongoing efforts to exploit GSK3β for its therapeutic potential in the control of infectious diseases, and the increasing evidence that specific pathogens target GSK3β-related pathways for immune evasion. [Trends Microbiol]
Visit our reviews page to see a complete list of reviews in the infectious disease research field.
Have we missed an important article or publication in Immunology of Infectious Disease News?
Click here to submit!
Comments or Suggestions? Submit your feedback here.