| Vaccine Study Reveals Link between Immunity and Cells’ Starvation Response |
Researchers studying immune responses to the yellow fever vaccine – one of the most effective in history – identified a gene whose activation in key immune cells is a sign of a robust response. The gene, called GCN2, encodes a protein involved in sensing amino acid starvation and regulates the process of autophagy, a response to starvation or stress within cells. [Press release from Emory University discussing online prepublication in Science] Abstract | Press Release
| Stem Cell Transplantation in the Context of HIV – How Can We Cure HIV Infection?|
In 2013, reports were published about a possible cure of HIV-infected individuals who received allogeneic bone marrow transplants with cells not resistant to HIV. The authors review these stem cell transplant procedures and discuss their utility to provide a cure for HIV infection, including efficacious future stem cell gene therapy applications. [Expert Rev Clin Immunol] Abstract
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